association of hypoproteinemia in preeclampsia with maternal and perinatal outcomes: a retrospective analysis of high?risk women

background: the aim of this study was to evaluate maternal and perinatal outcomes in preeclampsia (pe), according to the value of albumin.materials and methods: preeclamptic women were retrospectively divided into mild hypoproteinemia (mhp, n = 220) and severe hypoproteinemia (shp, n = 79) pe according to the value of albumin. the maternal and perinatal outcomes were evaluated in both groups. results: two hundred and ninety?nine single pregnancies complicated by pe were included in this study. gestational age at delivery was earlier in shp than mhp (p < 0.01). severe hypertension, abnormal liver function, abnormal renal function, ascites,and abruption occurred more frequently in shp than in mhp (p < 0.01, 0.03, <0.01, 0.01, and 0.04, respectively). women in shp had a higher rate of cesarean section than those in mhp (p = 0.04). fetal growth restriction infants were more frequent in shp than in mhp (p < 0.01). the occupancy rate of the neonatal intensive care unit was higher in shp than in mhp (p < 0.01). conclusion: shp pe is associated with a higher risk of adverse pregnancy outcome than mhp pe, deserving closer surveillance during pregnancy.